How cells specify morphologically distinct plasma membrane domains is poorly understood. Prior work has shown that restriction of microvilli to the apical aspect of epithelial cells requires the localized activation of the membrane-F-actin linking protein ezrin. Using an in vitro system. we now define a multi-step process whereby the kinase LOK specifically phosphorylates ezrin to act... https://www.chiggate.com/lovense-lush-3-supply/